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They need to be applied up to half an hour before sex, and a condom should be worn so that the anaesthetic is not absorbed by your partner. Some men report reduced sexual pleasure when using topical anaesthetics. Local allergic or irritant reactions are possible side effects. cialis malaysia Selective serotonin reuptake inhibitors SSRIs , a type of antidepressant, have been found to have delayed ejaculation as a side effect, and so are often used to treat premature ejaculation.